John P. Donohue, M.D. (1932–2008) graduated from Iona Preparatory School, New Rochelle, New York and Holy Cross College in Worchester, Massachusetts in 1954. He received his medical degree from Cornell University Medical College, completed initial surgical training at the New York Hospital and received his urologic training at Massachusetts General Hospital. After completing his training, he moved to Indianapolis, Indiana.

In 1971, he became Professor of Urology and Chairman of the Department at Indiana University School of Medicine, and eventually, Distinguished Professor Emeritus. He authored numerous articles on testicular cancer and pioneered new treatments, including the nerve-sparing technique. His work with Dr. Lawrence Einhorn led to an increase in cure rate of testicular cancer from 5% to 90%.